30th Marian Smoluchowski Symposium on Statistical Physics

Session

Session 6

5 Sept 2017, 14:00

Conveners

Session 6: Panel B

• Anna Ochab-Marcinek (Institute of Physical Chemistry, Polish Academy of Sciences)

6. Principles of design of artifical and biological molecular engines

Robert Holyst (Institute of Physical Chemistry PAS)

05/09/2017, 14:00

oral

Molecular engines are based on different principles than macroscopic motors. I will present two examples: artifical engine created in our lab namely nano-wind mill driven by evaporation of water and the motion of kinesin motor walking on microtubules. This biological engine, of incredibly efficiency, is driven by thermal noise, while consumption of ATP is mainly used for detachment of its...

88. Complex dynamics of genomic sites in the nucleus of live cells

Yuval Garini (Bar Ilan University)

05/09/2017, 14:30

oral

The DNA in a human cell is ~3 meters long. It is dynamic and yet is well organized. What are the mechanisms that organizes the chromatin and chromosomes in the nucleus? Using dynamic methods in live cells, we identified a mechanism that maintains the genome organization in the nucleus. We claim that lamin A forms chromatin loops by lamin A dimers (or oligomers) thereby restricting the...

116. Navigation and target search on human chromosomes

Ludvig Lizana (Umeå University)

05/09/2017, 15:00

oral

In living cells, proteins often bind to specific basepair sequences on DNA, such as transcription factor proteins that regulate gene expression, or restriction enzymes that cut the DNA at cleavage sites. These proteins search for targets that are about 10 basepairs long, on a DNA that is a few mega basepairs in bacteria, and billions in humans. This sounds like a needle in a haystack- problem...

24. Griffiths phases on a large human Open Connectome network

Geza Odor (MTA-EK-MFA, Research Center for Energy, Hungarian Academy of Sciences)

05/09/2017, 15:15

oral

Extended numerical simulations of threshold models have been performed on a human brain network with N=836733 connected nodes available from the Open Connectome Project [1]. While in the case of simple spreading models like contact process, SIS or threshold model a sharp discontinuous phase transition, without any critical dynamics arises, variable threshold models exhibit extended...